During physiological stress, hypotension, or severe infection, the hypothalamic-pituitary-adrenal (HPA) axis is activated. The hypothalamus secretes corticotrophin-releasing hormone (CRH) stimulating the release of adrenocorticotrophin hormone (ACTH) from the anterior pituitary.
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Tagged ‘Resuscitation’
Journal Review
ADRENAL – Corticosteroids in Septic Shock
Core
Petition to Retire the Surviving Sepsis Campaign Guidelines
This post is a multi-physician, multi-specialty petition detailing significant concerns with the surviving sepsis campaign guidelines.
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Core
Topics in Post-ROSC Care
This post explores controversial topics in post-ROSC care including the use of NCHCT, hemodynamic goals and cardiac catheterization
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Journal Review
IO vs. IV in Out-of-Hospital Cardiac Arrest (OHCA)
This Journal Review is cross-posted on REBEL EM.
Placement of vascular access for administration of resuscitation drugs and fluids is a common procedure in the management of out of hospital cardiac arrest (OHCA).
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Journal Review
Apneic Oxygenation in the ICU
Hypoxemia is the most common complication of endotracheal intubation in the critically ill and the strongest risk factor for periprocedural cardiac arrest and death. The traditional approach to avoiding desaturation during intubation is preoxygenation.
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Core
Acute Pancreatitis
This post explores the diagnosis and critical steps in the management of pancreatitis.
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Journal Review
Effect of US on CPR Pauses in Cardiac Arrest
The provision of high-quality compressions with minimal interruptions is central to the management of cardiac arrest. Along with defibrillation, high-quality compressions are the only interventions proven to improve patient-oriented outcomes.
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