Morbidity and mortality rates are high among adult patients with acute bacterial meningitis especially those with pneumococcal meningitis. Animal studies have shown that bacterial lysis occuring with antibiotic treatment leads to inflammation in the subarachnoid space and that treatment with dexamethasone,
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Tagged ‘Neurology’
Journal Review
Dexamethasone in Adults with Bacterial Meningitis
Journal Review
Levetiracetam versus Phenytoin for Second-Line Treatment of Convulsive Status Epilepticus in Children (ConSEPT): An Open-Label, Multicentre, Randomised Trial
Status epilepticus is associated with significant morbidity and mortality. Benzodiazepines are recommended as first line agents but their efficacy is approximately 50%. The most commonly recommended 2nd line agents are Phenytoin and Fosphenytoin.
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Core
Cauda Equina Syndrome
This post reviews the rare but high-associated morbidity diagnosis of cauda equina syndrome.
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Journal Review
Tenecteplase vs Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)
This review is cross-posted on REBEL EM.
Alteplase is a tissue plasminogen activator that is approved for use prior to thrombectomy in ischemic strokes with the goal of reperfusion to ischemic areas of the brain.
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Core
Wernicke Encephalopathy
This post explores Wernicke Encephalopathy with a focus on diagnosis and management.
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