This review is cross-posted on REBEL EM.
Alteplase is a tissue plasminogen activator that is approved for use prior to thrombectomy in ischemic strokes with the goal of reperfusion to ischemic areas of the brain.
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Tagged ‘Thrombolytics’
Journal Review
Tenecteplase vs Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)
Journal Review
Long-Term Outcomes in Submassive PE After Thrombolytics
There is scant evidence published on the long-term outcomes of systemic thrombolysis in acute submassive PE. Many advocate for the use of systemic thrombolysis to reduce morbidity (complications from chronic pulmonary hypertension) and mortality.
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Journal Review
NINDS – tPA in Ischemic Stroke
Each year, 22 million people worldwide will experience a stroke. 50% of these are ischemic strokes. For years, there were no effective treatments for these patients. As a result, the burden of ischemic stroke was enormous.
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Core
Hemodynamically Unstable Pulmonary Embolism
This posts delves into diagnosis + management of HD unstable (Massive) PE with a focus on thrombolytics.
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