Children with knee monoarthritis from Lyme disease and septic arthritis can have similar presentations. The early disseminated stage of Lyme disease, when knee monoarthritis would typically present, occurs 3-5 weeks post tick bite and a history of tick bite may not be present. In addition, synovial fluid cell counts do not distinguish between septic and Lyme arthritis and bacterial cultures and Lyme disease serology may take several days to result.
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Journal Review
Validation of Septic Knee Monoarthritis Prediction Rule in a Lyme Disease Endemic Area
Core
Neonatal Hypoglycemia
A deeper dive into one of THE MISFITS (Metabolic) as an etiology of the critically ill infant.
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Hand, Foot, and Mouth Disease
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