Core Journal Reviews

Filed Under: Tags: , , April 26th, 2018 Leave a Comment

The HEAVEN Difficult Airway Prediction Tool

This review was previously posted on REBEL EM here.

Predicting an anatomically and/or physiologically challenging airway is not a straightforward task by any stretch of the imagination.  There are some existing difficult-airway prediction tools available (i.e. LEMON = Look externally, Evaluate 3-3-2 rule, Mallampati score, Obstruction, Neck mobility), but many of them were derived in an elective surgery setting and may not be as applicable to emergency airway management. 
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Filed Under: Tags: , April 19th, 2018 Leave a Comment

PE Rule-Out Criteria RCT

The diagnosis of a pulmonary embolism (PE) in the Emergency Department (ED) is complicated. Many different decision rules have been developed to help risk stratify patients coming into the ED with some level of suspicion for PE.  The Pulmonary Embolism Rule-Out Criteria (PERC) are a set of decision rules created to reduce testing in patients who have a low probability of PE.
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Filed Under: Tags: , , , April 12th, 2018 Leave a Comment

Door-to-Furosemide Time

Acute congestive heart failure (AHF) results in nearly 1 million emergency department (ED) visits in the US per year and is associated with high morbidity, mortality, and cost.  It is increasingly clear that ED management of these patients may determine later in-hospital mortality and ultimate prognosis.
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Filed Under: Tags: , , April 5th, 2018 Leave a Comment

Utility of quick sepsis-related organ failure assessment (qSOFA) to predict outcome in patients with pneumonia

Pneumonia, an acute infection of the pulmonary parenchyma, is a disease that commonly presents to US Emergency Departments, with an incidence as high as 9.7 per 1000 persons in developed countries.  Studies have found that community acquired pneumonia alone has a hospitalization rate of 46.5% and 30-day mortality of 12.9%, with a case fatality rate of over 50% in patients with pneumonia-related sepsis/septic shock (Kolditz 2016, 
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Idarucizumab for Dabigatran Reversal II

Dabigatran is an oral direct thrombin inhibitor, touted as non-inferior to Warfarin (though there is some debate about its safety (Yao, Abraham et al. 2016, Hernandez, Baik et al. 2018). It is now routinely prescribed for the treatment of non-valvular atrial fibrillation, venous thromboembolism (VTE) and post-surgical prophylaxis. Dabigatran blocks the last stages of the coagulation cascade,
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IO vs. IV in Out-of-Hospital Cardiac Arrest (OHCA)

This Journal Review is cross-posted on REBEL EM.

Placement of vascular access for administration of resuscitation drugs and fluids is a common procedure in the management of out of hospital cardiac arrest (OHCA). While intravenous (IV) placement has been the standard approach for decades, intraosseous (IO) access is rapid and safe and may be the preferred approach due to fact that the bone marrow does not collapse during shock states as peripheral veins often do.
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Apneic Oxygenation in the ICU

Hypoxemia is the most common complication of endotracheal intubation in the critically ill and the strongest risk factor for periprocedural cardiac arrest and death. The traditional approach to avoiding desaturation during intubation is preoxygenation. However, in critically ill patients, acute physiologic abnormalities render preoxygenation less effective. Apneic oxygenation is the delivery of supplemental oxygen to the nasopharynx in the absence of ventilation.
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Performance of the Ottawa Heart Failure Risk Score

In the United States, heart failure affects 5.7 million people. Acute heart failure exacerbation is a common ED presentation and 1 in 9 deaths in the US included heart failure as a contributing cause. Each year it contributes to more than 1 million hospitalizations, and while in the past almost all patients with acute heart failure exacerbations were admitted,
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