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Wernicke Encephalopathy

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This post explores Wernicke Encephalopathy with a focus on diagnosis and management.
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Journal Review

Corticosteroids in Pharyngitis – Systematic Review + Meta-Analysis

Filed Under: Tags: , , May 31st, 2018 Leave a Comment

Sore throat is among the most common complaints in the emergency department (ED). Sometimes, the etiology is bacterial, and in those cases antibiotics may shorten the duration of disease and provide symptomatic relief. The majority of cases are viral and though most are appropriately treated with symptom management in the forms of NSAIDS and acetaminophen,
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Journal Review

Balanced Solutions vs 0.9% Saline in Critical Care (SMART)

Filed Under: Tags: , , , , , May 24th, 2018 Leave a Comment

Although 0.9% sodium chloride (“normal” saline) is traditionally the most commonly used intravenous fluid, it is unclear if “normal” saline is the best fluid. Data from prior studies suggests 0.9% saline use may result in hyperchloremic acidosis. Additionally, 0.9% saline is associated with the development of acute kidney injury (AKI). There have been several observational studies and a before-and-after trial comparing 0.9% saline and “balanced” crystalloids like lactated Ringer’s and Plasma-Ltye A,
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Disutility of Orthostatics in Volume Depletion

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This post delves into the utility of orthostatic vital signs in determining volume depletion or volume loss.
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Journal Review

The VAN Assessment to Identify Large Vessel Occlusion Strokes

Filed Under: Tags: , , May 17th, 2018 Leave a Comment

This review is cross-posted on REBEL EM.

Over the last three years, we have seen the rise of neurointerventional therapies for patients with ischemic strokes due to large vessel occlusions (LVOs). This group of strokes typically includes patients with occlusion of the distal intracranial carotid artery, middle cerebral artery or anterior cerebral artery.
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Post-Partum Hemorrhage

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This post explores post-partum hemorrhage with a focus on identification and management.
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Journal Review

SALT-ED: Balanced Solutions vs 0.9% Saline in the ED

Filed Under: May 10th, 2018 Leave a Comment

Intravenous fluid administration is a staple of modern medical care. The advantage of crystalloid over colloid solutions is well established in the literature. However, few studies have examined differences in outcomes between “normal” saline solution (0.9% NaCl) and more “balanced” solutions such a Ringer’s Lactate or Plasma-Lyte A, which seek to more closely replicate “physiologic” conditions.
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