Fever without source in infants less than three months old presents a difficult diagnostic dilemma for ED physicians. Over the past 25 years several algorithms have been developed to help guide clinicians, most notably the Rochester, Philadelphia and Boston Criteria, in determining which infants require admission vs. outpatient management. These studies were designed published between 1992 and 1994 prior to the wide spread use of HiB and pneumococcal vaccines in children,
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