While early recognition and treatment of sepsis has improved outcomes, mortality rates continue to be high. In low income countries, septic patients suffer mortality rates as high as 60%. Sepsis has been associated with vitamin c deficiency,
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In 2016 the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), redefined sepsis as life-threatening organ dysfunction caused by a dysregulated host response to infection. This group postulated that sepsis can be identified through an increase in Sequential Organ Failure Assessment (SOFA) score of at least 2 points.
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