Core Journal Reviews

Filed Under: Tags: , October 8th, 2015 Leave a Comment

Age Adjusted D-dimer in PE – The ADJUST-PE Study

 Background

Acute pulmonary embolism (PE) is a common disease associated with high degrees of morbidity and mortality. The D-dimer assay has the potential to be a valuable test in the workup of PE as it is sensitive for thrombus formation. Unfortunately, specificity is low and indiscriminate use can lead to increased advanced imaging.
Read More

Filed Under: Tags: , October 1st, 2015 Leave a Comment

Transesophageal Echo in Cardiac Arrest

Sudden cardiac arrest has very poor outcomes; less than 11% of patients in cardiac arrest in the Emergency Department survive to discharge from the hospital. The management of cardiac arrest is algorithmic because providers have limited tools at their disposal and limited knowledge of the patient’s past medical history. EKG is limited in its evaluation of cardiac function.
Read More

Filed Under: Tags: , September 24th, 2015 One Comment

Ottawa Aggressive Atrial Fibrillation Protocol

Atrial fibrillation (AF) is one of the most common dysrhythmias encountered in the ED. Patients with chronic AF often present with increased heart rates, chest pain and weakness among other presentations. However, it’s the patients with new onset AF that really peak our interest. Why? Well, the management of these patients is potentially exciting, filled with procedures and clearly debatable.
Read More

Filed Under: Tags: , September 17th, 2015 4 Comments

D-dimer in Aortic Dissection

Acute Aortic Dissection (AD) is an uncommon, but potentially fatal cardiovascular disorder with a mortality of 1-2% per hour. This requires rapid identification and diagnosis, however, there are a limited number of screening tools available. Currently three diagnostic studies are employed: CT, MRI and TEE. Unfortunately, these modalities are time consuming, carry the risk of radiation and contrast reactions (in the case of CT) and are not always accessible (i.e.
Read More

Filed Under: Tags: , , September 10th, 2015 2 Comments

Insulin Glargine in DKA

Diabetic ketoacidosis (DKA) is a diagnosis commonly encountered in the emergency department (ED), with the numbers of patients presenting in DKA rising. The increasing number of DKA patients has led to a concomitant rise in cost, with a substantial part of the cost related to intensive care unit (ICU) stay. Treatment of DKA involves correcting acidosis/electrolyte derangements,
Read More

Filed Under: Tags: , September 3rd, 2015 Leave a Comment

Revisiting the “Golden Hour” of Trauma

“The Golden Hour”, a widely accepted concept that transport of the trauma patient within the initial 60 minutes after injury purports better outcomes has little empiric evidence directly supporting this relationship between time and outcome.  While there have been many studies that suggest a survival benefit to shorter on-scene time and shorter transit time; most studies fail to substantiate a relationship.
Read More

Filed Under: Tags: , August 27th, 2015 Leave a Comment

ATLS: Archaic Trauma Life Support?

ATLS teaches inexperienced providers a systemic approach to trauma, with focus on stabilization and appropriate transfer of care. It is designed for providers who do not have much trauma exposure, not necessarily for providers who work in major trauma centers. This article reviews the scope of ATLS training and asks whether it is important or relevant for providers in major trauma centers.
Read More

Recurrent Visits for Kids with Serious Bacterial Infections

Sepsis and meningitis are rare but feared diagnoses in children, especially when they are unable to provide any meaningful history. Based upon available evidence, it can be assumed that delayed diagnosis in a dangerous condition would lead to worse outcomes. Children under the age of one month are almost universally treated as if they are immunosuppressed for this reason,
Read More