Core Journal Reviews

Predictive Factors for Rebleeding in Aneurysmal Subarachnoid Hemorrhage

In patients with subarachnoid hemorrhage, one of the major early complications is rebleeding, with reported incidences ranging from 8% to 23% in the first 72 hours (Larsen 2010).  If repair of the ruptured aneurysm is performed successfully in a timely fashion, the chance of rebleeding can be decreased, thereby decreasing morbidity and mortality in these patients. 
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Age-Adjusted D-dimer (Using D-dimer Units)

Risk stratification tools like the Well’s and Geneva scores are useful for identifying patients in whom a venous thromboembolism (VTE) can be excluded with a negative D-dimer. This allows for decreased utilization of computed tomographic pulmonary angiography, V/Q scans and lower limb ultrasounds. However, the poor specificity of the D-dimer is associated with more patients getting imaged and the increased identification of sub-segmental clots of questionable significance.
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Effectiveness of Diazepam Adjunct Therapy in Acute Low Back Pain

Thanks to Salim Rezaie for the peer review. This post is cross-posted at REBEL EM.

Low back pain is an extremely common presentation to US Emergency Departments (EDs) representing 2.4% or 2.7 million visits annually. The vast majority of presentations are benign in etiology but can be time consuming and frustrating for both patients and physicians.
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Observation Units Reduce Admissions and Discharges Home

Observation units (OUs) are a hot topic in Emergency Medicine (EM) today. They are expanding their presence among hospitals, and their footprint within hospitals, every day (Feng 2013). The reason for this is multifactorial, but is almost always a response to cost and policy challenges. First, OUs present reductions in cost for hospitals, as they are cheaper than full inpatient stays and often include shorter length of stays.
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Acute Kidney Injury is not Associated with IV Contrast Use in the ED

Intravenous (IV) iodinated contrast media is used routinely to improve the accuracy of computed tomography (CT) in the emergency department (ED).  Prior studies have linked contrast media with the development of acute kidney injury (AKI) and has been linked to increased risk of major adverse events including the initiation of dialysis, renal failure, stroke, myocardial infarction and death.  
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Validation of qSOFA for Mortality Prediction in the ED

In 2016 the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), redefined sepsis as life-threatening organ dysfunction caused by a dysregulated host response to infection. This group postulated that sepsis can be identified through an increase in Sequential Organ Failure Assessment (SOFA) score of at least 2 points. The quick SOFA (qSOFA) score is a simplified tool that includes respiratory rate >21 breaths/min,
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Racial/Ethnic and Insurer Disparities in Academic Medical Centers

Academic medical centers (AMC) are often viewed as providing exceptional patient care and are often among the top ranked hospitals in the country. While historically they have provided significant care to uninsured and Medicaid patients, there is concern of a trend of decreasing care at AMCs for such patients. 
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30-Day Outcomes After Aggressive AF Management in the ED

Atrial fibrillation (AF) is one of the most common dysrhythmias encountered in the ED. The management of recent-onset AF and atrial flutter (AFl) in the ED continues to be debated. The discussion centers on whether patients with recent-onset AF should be rhythm controlled (e.g. converted back to sinus rhythm) or rate controlled only. This debate was showcased in a point-counterpoint in Annals of Emergency Medicine in 2011 (Stiell 2011,
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